Botulinum toxin

Botulinum toxin is a safe, patented drug that temporarily relaxes the mimic muscles of the face, preventing, or reducing the formation of, unsightly frown lines.

Botulinum toxin is the ideal treatment for those who want to minimize the so-called expression lines (or dynamic wrinkles) of the upper part of the face, especially the forehead and periocular region, and for the treatment of wrinkles that form between the eyebrows (glabellar wrinkles). It is injected through the use of a very thin needle and no anesthesia is required.

It has been used for many years in various medical disciplines (maxillofacial surgery, neurology, ophthalmology) in particular for the treatment of spasmodic torticollis, spastic tetraparesis and blepharospasm.

Specifically, the botulinum toxin acts at the level of the neuromuscular plate inducing the selective temporary blockade of the release of acetylcholine (ACh), mediator responsible for transmitting the signal of muscle contraction or at the level of sweat glands to produce sweat.

Its action at the muscular level aims to decrease the tone of the muscles without causing the complete paralysis and at the level of the sweat glands to interrupt the transmission of the stimulus to the production of sweat.



  • glabellar and periocular wrinkles
  • off label use
  • frontal wrinkles
  • perinasal “bunny lines” wrinkles
  • neck and décolleté wrinkles and platysmal bands
  • barcode” upper lip wrinkles


Face, neck, hands and armpits


The session generally lasts a few minutes and the toxin is injected by the doctor with fine needles. No anesthetic is required as the procedure is virtually painless. The therapeutic effect generally appears after 1-3 days to peak at 1-3 weeks and reach a plateau at 30-45 days. Subsequently, the effect decreases until it disappears completely in a period varying from 3 to 6 months. In case the results are optimal, a second treatment is possible at a distance of 15 days after which for 4 months the toxin should not be repeated.


The day of treatment is required:

  • avoid physical activity
  • avoid exposure to the sun or UV rays
  • avoid exposure to prolonged heat sources (long, very hot showers, Turkish baths, saunas) or prolonged cold for the 4 weeks following treatment
  • avoid traumatizing maneuvers such as gumming, brushing, rubbing
  • the use of inappropriate detergents and cosmetics can increase the risk of side effects and alter the final aesthetic result


Se vuoi saperne di più sulla Mesoterapia vieni a trovarci presso il Poliambulatorio Estemed della Dottoressa Paola Rosalba Russo in Str. Saliceto Panaro, 123, 41122 Modena.

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Mon, Tue and Thu from 9.00 am to 8.00 pm
Friday from 9.00 a.m. to 6.00 p.m.
Wednesday, Saturday and Sunday closed